Yoon Seok Kim

The paper identifies selective vulnerability of dopamine-glutamate neurons in aging as a mechanism weakening entorhinal dopamine signaling.

This study identifies the NLGN3-CSPG4-PIEZO1 axis as a regulator of glial precursor cell state and glioma proliferation through mechanosensitive signaling.

The paper identifies two lineage-committed progenitors in the developing brain that generate forebrain/midbrain and hindbrain regions, and demonstrates their distinct chromatin landscapes and differentiation potential.

This study shows that cholinergic neuron activity promotes both healthy OPC and DMG proliferation through muscarinic receptors, with specific nuclei driving growth in different brain regions.

This study identifies how different subtypes of VTA glutamatergic neurons signal reward and aversion in distinct ways, highlighting unique roles in behavioral salience.

This study identifies functional GABAergic neuron-to-glioma synapses in diffuse midline gliomas that promote tumor proliferation and shows that drugs modulating GABAergic signaling affect glioma growth.

This study identifies monosynaptic inputs to VTA VGluT2+VGaT+ neurons in mice, revealing diverse brain-wide connections and distinct behavioral outcomes from lateral hypothalamus and superior colliculus inputs.

The paper shows that vmPFC Dyn neurons suppress defensive behaviors by releasing dynorphin in response to threats and promoting fear-related network states.

This study shows that BDNF-TrkB signaling promotes malignant synaptic plasticity in gliomas, enhancing tumor progression through mechanisms similar to long-term potentiation in the healthy brain.

This study identifies VGLUT-mediated mechanisms protecting DA neurons from PD-related degeneration, revealing sex-specific effects and transcriptional regulators.

The paper identifies three genetic dopamine subtypes in the substantia nigra pars compacta, each with distinct functional responses to rewards, aversive stimuli, and movement, showing strong correlation between soma and axon signaling within subtypes.

The paper shows that somatic and axonal signaling in dopamine neurons of behaving mice are correlated, challenging previous assumptions about axonal autonomy.