Author

Maria Serena Paladini

University of California, San FranciscoORCID 0000-0001-7320-6622Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Assay:imaging· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Elma S. FriasiD· 3 shared Karen KrukowskiiD· 3 shared Susanna RosiiD· 3 shared Amber NolaniD· 2 shared Gonzalo UretaiD· 2 shared Katherine A. Grue· 2 shared Peter WalteriD· 2 shared Benjamin A. YangiD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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3 shared papersNeuroscience

Elma S. FriasORCID

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3 papers

Recent·Most cited

ImmunologyNature CommunicationsPeer-reviewedOct 7, 2025

Fate mapping of peripherally derived macrophages reveals a long-lasting engrafted population that maintains a distinct transcriptomic profile for up to 8 months after Traumatic Brain Injury

Maria Serena Paladini, Benjamin A. Yang, Kristof A. Torkenczy…·Susanna Rosi

This study tracks the fate of monocyte-derived macrophages (MDMs) after traumatic brain injury (TBI) and finds they persist in the brain for up to 8 months, maintaining a distinct transcriptomic profile and phagocytic activity.

19 citationstop 1%

mousebulk RNA-seq

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NeuroscienceProceedings of the National Academy of SciencesPeer-reviewedOct 13, 2022

Aberrant cortical spine dynamics after concussive injury are reversed by integrated stress response inhibition.

Elma S. Frias, Mahmood S. Hoseini, Karen Krukowski…·Susanna Rosi

This study shows that inhibiting the integrated stress response (ISR) after concussive injury reverses cognitive deficits and aberrant cortical spine dynamics in mice.

18 citations

mouseimaging

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NeuroscienceeLifePeer-reviewedNov 30, 2020

Small molecule cognitive enhancer reverses age-related memory decline in mice.

Karen Krukowski, Amber Nolan, Elma S. Frias…·Susanna Rosi

Inhibition of the integrated stress response restores neuronal and immune dysfunction and alleviates memory deficits in aged mice.

170 citationstop 2%

mouseexperimental assay

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