Author

Hicham Bessaiah

McGill UniversityORCID 0000-0001-7333-2581Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Approach:experimental assay· 2 Organism:mouse· 2 Approach:deep learning· 1 Research Focus:differential expression· 1 Organism:E. coli· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Adam MacDonaldiD· 2 shared Alexandra KazanovaiD· 2 shared Heidi May McBrideiD· 2 shared Jessica PeiiD· 2 shared Jo Anne StrattoniD· 2 shared Samantha GruenheidiD· 2 shared Sherilyn Junelle RecintoiD· 2 shared Alexis AllotiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersImmunology

Adam MacDonaldORCID

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3 papers

Recent·Most cited

MicrobiologybioRxivPreprintOct 19, 2026

Amino Sugar Metabolism with AgaSY Coordinates Carbon Catabolism, Fimbrial Regulation, and Pathogenesis in Uropathogenic E. coli

Carole Anamalé, Hicham Bessaiah, Sébastien Houle…·Charles Martin Dozois

This study identifies agaSY genes in UPEC as essential for amino sugar catabolism and links their loss to reduced virulence and colonization in a murine model.

DOI 10.64898/2026.10.16.759770

E. coliexperimental assay

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Immunologynpj Parkinson s DiseasePeer-reviewedMay 22, 2025

A rewiring of the earliest immune events leading to T-cell mediated disease following intestinal infection in a PINK1 knock out mouse model of Parkinsons disease

Sherilyn Junelle Recinto, Alexandra Kazanova, Lin Liu…·Jo Anne Stratton

This study identifies early immune dysregulation in PINK1 KO mice following intestinal infection, showing myeloid cell activation and T cell response as key factors in PD-like disease progression.

11 citationstop 3%

mousescRNA-seq

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ImmunologybioRxivPreprintFeb 25, 2024

Modeling gene-environment interactions in Parkinson's Disease: Helicobacter pylori infection of Pink1-/- mice induces CD8 T cell-dependent motor and cognitive dysfunction.

Alexandra Kazanova, Jacqueline Sung, Nathalia Oliveira…·Samantha Gruenheid

This study shows that Helicobacter pylori infection in Pink1-/- mice causes motor and cognitive dysfunction linked to CD8 T cell activity, mimicking early PD features.

3 citations

mouseexperimental assay

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