Author

Jessica Pei

Aligning Science Across Parkinson'sORCID 0000-0001-7115-5606Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Organism:mouse· 3 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:scRNA-seq· 2 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

Alexandra KazanovaiD· 3 shared Jo Anne StrattoniD· 3 shared Samantha GruenheidiD· 3 shared Sherilyn Junelle RecintoiD· 3 shared Adam MacDonaldiD· 2 shared Heidi May McBrideiD· 2 shared Hicham BessaiahiD· 2 shared Michel DesjardinsiD· 2 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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3 shared papersImmunology

Alexandra KazanovaORCID

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3 papers

Recent·Most cited

Immunologynpj Parkinson s DiseasePeer-reviewedAug 29, 2025

LRRK2 G2019S mutation incites increased cell-intrinsic neutrophil effector functions and intestinal inflammation in a model of infectious colitis

Jessica Pei, Nathalia Luisa Oliveira, Sherilyn Junelle Recinto…·Samantha Gruenheid

This study shows that the LRRK2 G2019S mutation enhances neutrophil effector functions and drives intestinal inflammation in a mouse model of infectious colitis.

4 citations

mousescRNA-seq

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Immunologynpj Parkinson s DiseasePeer-reviewedMay 22, 2025

A rewiring of the earliest immune events leading to T-cell mediated disease following intestinal infection in a PINK1 knock out mouse model of Parkinsons disease

Sherilyn Junelle Recinto, Alexandra Kazanova, Lin Liu…·Jo Anne Stratton

This study identifies early immune dysregulation in PINK1 KO mice following intestinal infection, showing myeloid cell activation and T cell response as key factors in PD-like disease progression.

11 citationstop 3%

mousescRNA-seq

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ImmunologybioRxivPreprintFeb 25, 2024

Modeling gene-environment interactions in Parkinson's Disease: Helicobacter pylori infection of Pink1-/- mice induces CD8 T cell-dependent motor and cognitive dysfunction.

Alexandra Kazanova, Jacqueline Sung, Nathalia Oliveira…·Samantha Gruenheid

This study shows that Helicobacter pylori infection in Pink1-/- mice causes motor and cognitive dysfunction linked to CD8 T cell activity, mimicking early PD features.

3 citations

mouseexperimental assay

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