Author

Roxanne Perez‐Tremble

University of PennsylvaniaORCID 0009-0001-0609-3100Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Genetics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Annabel K. SangreeiD· 1 shared Brittany C. ClawsoniD· 1 shared Daniel TorresiD· 1 shared Donald S. Popke· 1 shared Drew WeissmaniD· 1 shared Emily R. FeiermaniD· 1 shared Erica KorbiD· 1 shared Honghong Sun· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperGenetics

Annabel K. SangreeORCID

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3 papers

Recent·Most cited

GeneticsbioRxivPreprintApr 22, 2026

Mechanisms controlling the deposition and dynamics of histone variant H2BE

Annabel K. Sangree, Emily R. Feierman, Roxanne Perez‐Tremble, Erica Korb

This paper identifies key factors regulating H2BE incorporation, localization, and eviction in neuronal chromatin, revealing chaperones and complexes involved in its dynamics.

DOI 10.64898/2026.04.20.719605

mouseChIP-seq

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BioengineeringbioRxivPreprintOct 17, 2025

Anionic lipids modulate mRNA-lipid nanoparticle immunogenicity and confer protection in a mouse model of multiple sclerosis

Jilian R. Melamed, Jenna Muscat-Rivera, Michael Kegel…·Drew Weissman

This study shows that anionic lipids in mRNA-LNPs can modulate immune responses, reducing inflammation and disease in a multiple sclerosis mouse model.

5 citations

mousebulk RNA-seq

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NeurosciencebioRxivPreprintJul 14, 2023

Hypnotic treatment reverses NREM sleep disruption and EEG desynchronization in a mouse model of Fragile X syndrome to rescue memory consolidation deficits.

Jessy D. Martinez, Lydia G. Wilson, William P. Brancaleone…·Sara J. Aton

4 citations

mouseelectronic health records

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