Guihua Sun

The paper investigates sliDRNAs, DNA nucleotide-substituted sliced-siRNAs, to understand their processing, maturation, and silencing mechanisms compared to siRNA and insights into Ago2 slicing actions.

BRIDGE-AD integrates multimodal AD datasets to prioritize disease effectors, identifying 19 functional clusters and validating SCARB2 as a novel candidate.

The paper analyzes long-term cultured human islets to identify gene expression changes and cellular dynamics, revealing transdifferentiation and dedifferentiation processes.

The paper reassesses miRNA abundance in human pancreas and rodent cell lines, finding miR-148a-3p and miR-7-5p are equally abundant in islets, challenging the previous notion of miR-375-3p as the dominant miRNA.