Meirigeng Qi

Harmine Plus Exendin-4 Enhances Remission of Recent-Onset Type 1 Diabetes Following Anti-CD3 Therapy

This study shows that harmine plus exendin-4, when combined with anti-CD3 therapy, promotes beta-cell recovery and reduces immunogenicity, leading to remission of recent-onset type 1 diabetes.

Mapping Endothelial-Macrophage Interactions in Diabetic Vasculature: Role of TREM2 in Vascular Inflammation and Ischemic Response

This study maps endothelial-macrophage interactions in diabetic vasculature using single-cell and spatial transcriptomics, identifying TREM2 as a key driver of vascular inflammation and ischemic response in diabetes.

Multi-omics analysis of long-term cultured human islets

The paper analyzes long-term cultured human islets to identify gene expression changes and cellular dynamics, revealing transdifferentiation and dedifferentiation processes.

Reassessing the abundance of miRNAs in the human pancreas and rodent cell lines and its implication

The paper reassesses miRNA abundance in human pancreas and rodent cell lines, finding miR-148a-3p and miR-7-5p are equally abundant in islets, challenging the previous notion of miR-375-3p as the dominant miRNA.