Jan M. Ache

This study identifies a dedicated brain circuit in Drosophila that controls forward walking by initiating movement and modulating speed, independent of turning behaviors.

The paper compares neuronal circuits for landing and takeoff in Drosophila, revealing parallel ensembles that enable flexible behavioral control.

The paper identifies two neuronal populations in Drosophila that control distinct aspects of walking direction on different hierarchical levels, showing their activity correlates with specific turning behaviors.

This study shows that peroxisomes interact with the Golgi in Drosophila insulin-producing cells to regulate sphingolipid composition and support insulin-like peptide secretion.

The paper investigates how neuromodulatory inputs control insulin-producing cells in Drosophila using single-nucleus RNA sequencing, connectomics, and electrophysiology, revealing heterogeneous receptor profiles and differential modulation.

The paper investigates how nutritional state modulates insulin-producing cells (IPCs) in Drosophila, showing that IPC activity is influenced by starvation, refeeding with nutritive sugars, and interactions with other neurons.