Author

Keeley Spiess

Florida Atlantic UniversityORCID 0000-0001-7357-4337Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Adele StewartiD· 1 shared Alexey KozlenkoviD· 1 shared Angelica E. Wiggins· 1 shared Benxia HuiD· 1 shared Bibi S. Kassim· 1 shared Cheynna CrowleyiD· 1 shared Daniel H. GeschwindiD· 1 shared Faakhira A. Diljohn· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperNeuroscience

Adele StewartORCID

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3 papers

Recent·Most cited

Autism-related behavioral phenotypes of three Camk2a mutant mouse lines with reduced CaMKIIalpha expression and/or activity

Jessica R. Thomas, Keeley Spiess, Roger J. Colbran

This study compares behavioral phenotypes of three Camk2a mutant mouse lines with reduced CaMKII expression or activity, finding increased stereotypic jumping, hyperactivity, and reduced tactile sensitivity across all lines.

bioRxiv · Oct 28, 2022 · PreprintNeuroscience

Sex and Circuit Specific Dopamine Transporter Regulation Underlies Unique Behavioral Trajectories of Functional SLC6A3 Coding Variation

Adele Stewart, Felix P. Mayer, Raajaram Gowrishankar, Gwynne L. Davis, Lorena Bianchine Areal, Paul J. Gresch, Rania M. Katamish, Rodeania Peart, Samantha E. Stilley, Keeley Spiess, Maximilian J. Rabil, Faakhira A. Diljohn, Angelica E. Wiggins, Roxanne A. Vaughan, Maureen K. Hahn, Randy Blakely

The paper investigates sex-specific effects of a dopamine transporter variant on behavior and identifies sex-dependent circuit-specific regulation of dopamine signaling.

bioRxiv · Nov 2, 2021 · PreprintNeuroscience

Neuronal and glial 3D chromatin architecture illustrates cellular etiology of brain disorders

Benxia Hu, Hyejung Won, Won Mah, Royce Park, Bibi S. Kassim, Keeley Spiess, Alexey Kozlenkov, Cheynna Crowley, Sirisha Pochareddy, Yun Li, Stella M. Dracheva, Nenad Šestan, Schahram Akbarian, Daniel H. Geschwind

The paper integrates chromatin architecture with transcriptomic data to explore cell-type-specific gene regulatory networks in brain disorders, identifying distinct cellular contributions to Alzheimer's and psychiatric diseases.

bioRxiv · May 14, 2020 · PreprintNeuroscience