T-cell commitment inheritance - an agent-based multi-scale model
Emil Andersson, Ellen V. Rothenberg, Carsten Peterson, Victor Olariu
The paper develops an agent-based model to study T-cell commitment timing and inheritance, showing a three-step process with transcriptional preparation, loss of Bcl11b-opposing function, and DN2b state transition.
npj Systems Biology and Applications · Apr 17, 2024Peer-reviewedSystems Biology