Systems BiologyCell ReportsPeer-reviewed
Multi-scale dynamical modelling of T-cell development from an early thymic progenitor state to lineage commitment
Victor Olariu, Mary A. Yui, Pawel Krupinski…·Carsten Peterson
The paper develops a multi-scale dynamic model of T-cell development, incorporating gene regulatory networks, epigenetic gates, and proliferation kinetics to simulate commitment dynamics.
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