Emil Andersson

This paper identifies Hic2 as a gene that enhances iPSC generation by suppressing KLF4-dependent epidermal gene expression during reprogramming.

This paper describes a method to generate human parvalbumin interneurons from glial precursor cells using direct reprogramming and identifies a distinct transcriptional profile and reprogramming trajectory.

The paper develops an agent-based model to study T-cell commitment timing and inheritance, showing a three-step process with transcriptional preparation, loss of Bcl11b-opposing function, and DN2b state transition.

CELLoGeNe maps Boolean gene regulatory networks into energy landscapes to analyze cell fate decisions, identifying attractors in pluripotency maintenance and reprogramming.

The paper develops a multi-scale dynamic model of T-cell development, incorporating gene regulatory networks, epigenetic gates, and proliferation kinetics to simulate commitment dynamics.