Nataliya Safronova

The paper presents a cell-free system for studying Sec translocon function, identifies super-active variants, and demonstrates applications in improving membrane protein and nanobody export.

This study uses calorimetry to show how lipidome changes affect metabolic efficiency and growth in JCVI-Syn3B cells, revealing lipid-dependent entropic costs of division.

This study shows that a minimal cell membrane with two lipid species can support life, highlighting the importance of acyl chain diversity over head group diversity.

The paper uses chemically defined lipid diets to study how lipidome complexity affects membrane function and cell phenotypes in minimal cells.