Karim Fahmy

Membrane mimetics control internal hydration and catalytic activity of the copper ATPase LpCopA from Legionella pneumophila

This study shows that the membrane environment modulates internal hydration and catalytic activity of LpCopA, with hydration levels affecting ATPase function.

Metabolic heat flow from the minimal cell JCVI-Syn3B reveals the lipidome-dependence of growth and metabolism

This study uses calorimetry to show how lipidome changes affect metabolic efficiency and growth in JCVI-Syn3B cells, revealing lipid-dependent entropic costs of division.

X-ray Spectroscopy Meets Native Mass Spectrometry: Probing Gas-phase Protein Complexes

This paper discusses the use of X-ray spectroscopy and native mass spectrometry to study gas-phase protein complexes, showing fragmentation and dissociation patterns under different activation methods.

Chemically defined lipid diets reveal the versatility of lipidome remodeling in genomically minimal cells

The paper uses chemically defined lipid diets to study how lipidome complexity affects membrane function and cell phenotypes in minimal cells.