Angela Bellini

This study shows that ATRX mutation type affects chromatin response to retinoic acid in neuroblastoma, influencing differentiation and therapeutic response.

This study develops a Tumor-on-Chip platform for rapid drug testing in breast cancer, showing high concordance with patient-derived xenografts and potential for clinical use.

The paper introduces QuantumClone, a method for clonal reconstruction in cancer that accounts for variant allele frequencies and genotypes, and applies it to neuroblastoma samples to identify recurrently altered pathways in different clonal populations.