Author

Sarah Hoosdally

University of OxfordORCID 0000-0001-7375-6907Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Assay:whole-genome sequencing· 3 Organism:human· 2 Organism:bacteria (other)· 1 Approach:experimental assay· 1 Research Focus:genome assembly· 1 Research Focus:variant calling· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Derrick W. CrookiD· 4 shared Tim PetoiD· 4 shared Ann Sarah WalkeriD· 3 shared Ajit LalvaniiD· 2 shared Alexander S. LachapelleiD· 2 shared Ana Lúıza Gibertoni CruziD· 2 shared Anastasia Sideris KochiD· 2 shared Andrea Maurizio CabibbeiD· 2 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersGenomics

Derrick W. CrookORCID

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4 papers

Recent·Most cited

Quantitative measurement of antibiotic resistance in Mycobacterium tuberculosis reveals genetic determinants of resistance and susceptibility in a target gene approach

Ivan Barilar, Simone Battaglia, Emanuele Borroni, Angela Pires Brandão, Alice E. Brankin, Andrea Maurizio Cabibbe, Joshua J. Carter, Darren Chetty, Daniela María Cirillo, Pauline Claxton, David A. Clifton, Ted Cohen, Jorge Coronel, Derrick W. Crook, Viola Dreyer, , Guy Edward Thwaites

This study quantifies antibiotic resistance in tuberculosis using genomic data and MIC measurements to identify genetic determinants of resistance and hypersensitivity across multiple drugs.

Nature Communications · Jan 12, 2024Peer-reviewedGenomics

Genomic network analysis of an environmental and livestock IncF plasmid population

William Matlock, Kevin Chau, Manal AbuOun, Emma J. Stubberfield, Leanne Barker, James Kavanagh, Hayleah Pickford, Daniel Gilson, Richard Piers Smith, Hyun S. Gweon, Sarah Hoosdally, Jeremy Swann, Robert Sebra, Mark Bailey, Tim Peto, , Liam P. Shaw

The paper analyzes IncF plasmid diversity across environmental and livestock settings using network community analysis, revealing niche-driven partitioning and core gene-defined communities.

bioRxiv · Jul 24, 2020 · PreprintBioinformatics

GenomegaMap: within-species genome-wide dN/dS estimation from over 10,000 genomes

Daniel J. Wilson, Derrick W. Crook, Tim Peto, Ann Sarah Walker, Sarah Hoosdally, Ana Lúıza Gibertoni Cruz, Joshua J. Carter, Clara Grazian, Sarah G. Earle, Samaneh Kouchaki, Alexander S. Lachapelle, Yang Yang, David A. Clifton, Philip William Fowler, Zamin Iqbal, , Dick van Soolingen

GenomegaMap estimates genome-wide dN/dS ratios across 10,209 tuberculosis genomes to identify selection pressures shaping the pathogen's evolution.

Molecular Biology and Evolution · Mar 10, 2020Peer-reviewedGenomics

Comparison of long-read sequencing technologies in the hybrid assembly of complex bacterial genomes

Nicola De Maio, Liam P. Shaw, Alasdair T. M. Hubbard, Sophie A. George, Nicholas D. Sanderson, Jeremy Swann, Ryan R. Wick, Manal AbuOun, Emma J. Stubberfield, Sarah Hoosdally, Derrick W. Crook, Tim Peto, Anna E. Sheppard, Mark Bailey, Daniel S. Read, , Nicole E Stoesser

This study compares hybrid assemblies of bacterial genomes using Illumina and long-read sequencing technologies, finding that combining ONT and Illumina reads provides high-quality, low-cost genome reconstruction.

Microbial Genomics · Sep 1, 2019Peer-reviewedBioinformatics