Author

Anastasia Sideris Koch

University of Cape TownORCID 0000-0002-5897-4196Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:whole-genome sequencing· 3 Organism:human· 2 Approach:statistical model· 2 Research Focus:variant calling· 2 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Ajit LalvaniiD· 2 shared Alexander S. LachapelleiD· 2 shared Ana Lúıza Gibertoni CruziD· 2 shared Andrea Maurizio CabibbeiD· 2 shared Andrea SpitaleriiD· 2 shared Arash GhodousiiD· 2 shared Camilla S RodriguesiD· 2 shared Chunfa LiuiD· 2 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenomics

Ajit LalvaniORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Mycobacteriophage D29-mediated lysis improves recovery of mycobacterial genomic DNA from low-biomass samples

Joseph Wambugu Gitari, Anastasia Sideris Koch, Elizabeth Kigondu, Digby Francis Warner, Mandy K. Mason

This paper demonstrates that mycobacteriophage D29-mediated lysis improves genomic DNA recovery from low-biomass mycobacterial samples compared to the CTAB method.

bioRxiv · Aug 9, 2026 · PreprintMicrobiology

Quantitative measurement of antibiotic resistance in Mycobacterium tuberculosis reveals genetic determinants of resistance and susceptibility in a target gene approach

Ivan Barilar, Simone Battaglia, Emanuele Borroni, Angela Pires Brandão, Alice E. Brankin, Andrea Maurizio Cabibbe, Joshua J. Carter, Darren Chetty, Daniela María Cirillo, Pauline Claxton, David A. Clifton, Ted Cohen, Jorge Coronel, Derrick W. Crook, Viola Dreyer, , Guy Edward Thwaites

This study quantifies antibiotic resistance in tuberculosis using genomic data and MIC measurements to identify genetic determinants of resistance and hypersensitivity across multiple drugs.

Nature Communications · Jan 12, 2024Peer-reviewedGenomics

GenomegaMap: within-species genome-wide dN/dS estimation from over 10,000 genomes

Daniel J. Wilson, Derrick W. Crook, Tim Peto, Ann Sarah Walker, Sarah Hoosdally, Ana Lúıza Gibertoni Cruz, Joshua J. Carter, Clara Grazian, Sarah G. Earle, Samaneh Kouchaki, Alexander S. Lachapelle, Yang Yang, David A. Clifton, Philip William Fowler, Zamin Iqbal, , Dick van Soolingen

GenomegaMap estimates genome-wide dN/dS ratios across 10,209 tuberculosis genomes to identify selection pressures shaping the pathogen's evolution.

Molecular Biology and Evolution · Mar 10, 2020Peer-reviewedGenomics