Amalia M. Dolga

This study presents a one-step protocol to differentiate hiPSCs into functional astrocytes, enabling co-culture with neurons to support network development.

This study compares how influenza A virus and human adenovirus type C5 induce ferroptosis-like features in lung epithelial cells, revealing similar lipid peroxidation and mitochondrial changes.

This study shows diesel exhaust particles impair microglial function and amyloid-beta clearance in both mouse and human models, potentially contributing to Alzheimer's disease progression.

The paper develops a label-free method to track morphological changes in iPSC-derived microglia over time and identifies stimulus-specific morphological responses.

This study characterizes a human neuronal model of CACNA1A haploinsufficiency, revealing synaptic deficits and increased intrinsic excitability linked to reduced potassium channel function.

This paper develops an in vitro model of human airway cholinergic neurons from pluripotent stem cells to study neuroplasticity in respiratory diseases.

The paper shows that BID interacts with VDAC1 to mediate mitochondrial permeabilization and neuronal cell death in response to stress.

The paper uses a fibroblast-specific genome-scale model to identify metabolic imbalances in Refsum disease, highlighting amino acid metabolism changes.