Thomas van Emden

This study identifies domain-specific heterochromatin regulators in Schizosaccharomyces pombe using quantitative methods and genetic screening, revealing Dhm2's role in heterochromatin maintenance and replication fidelity.

This study shows Lem2, an inner nuclear membrane protein in S. pombe, recruits exosome co-factors to the nuclear periphery to regulate RNA degradation and coordinate transcripts during the mitosis-to-meiosis switch.

The paper shows that subtelomeric sequences in S. pombe are hyper-recombinogenic and have unstable nucleosomes, with Ccq1 protecting them through heterochromatic repression.