Author

Alessia Piergentili

Forschungszentrum JülichORCID 0009-0001-2411-4825Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:electrophysiology· 1 Approach:mechanistic / dynamical model· 1

Frequent Co-Authors

Giulia RossettiiD· 2 shared Angelika LampertiD· 1 shared Anne Kaiser· 1 shared Axel ChoidasiD· 1 shared Bert KlebliD· 1 shared Deborah ChristeniD· 1 shared Heidi E. GreulichiD· 1 shared Hubert SchorleiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCancer Biology

Giulia RossettiORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintAug 18, 2026

PDE3A-SLFN12 Molecular Glues Target Multiple KIT D816V Cell Types in Preclinical Models of Mast Cell Malignancies

Xuhuang Fu, Anne Kaiser, Payal Chawla…·Martin Zenke

This paper identifies PDE3A-SLFN12 molecular glues as a novel therapeutic target for KIT D816V-driven mast cell malignancies, showing their efficacy in killing multiple KIT D816V cell types and synergy with tyrosine kinase inhibitors.

DOI 10.64898/2026.08.13.744624

humanproteomics

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PhysiologyInternational Journal of Biological MacromoleculesPeer-reviewedAug 7, 2024

Depletion of membrane cholesterol modifies structure, dynamic and activation of Nav1.7

Simone Albani, Vishal Sudha Bhagavath Eswaran, Alessia Piergentili…·Giulia Rossetti

This study shows that cholesterol depletion alters Nav1.7 structure and function, affecting its gating and drug response, with implications for pain management.

10 citations

humanelectrophysiology

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