Pau Bernadó

This study evaluates five computational methods for modeling conformational ensembles of flexible multidomain proteins using SAXS data, highlighting discrepancies and biases in their predictions.

This paper presents a generative framework for designing intrinsically disordered proteins using protein language models, showing that large datasets are essential for accurate conformational control.

The paper uses solution scattering and simulations to show that Dhh1's modular architecture allows structural heterogeneity while maintaining functional specificity.

This study reveals how DNA sequence and ligand binding influence the structural dynamics of RAR/RXR-coregulator complexes through integrative structural analysis.

The paper reanalyzes data from Rosenberg et al. to show that codon usage has no significant effect on dihedral angles in protein structures.

This study investigates how intrinsically disordered proteins modulate the optical properties of gold nanoclusters through position-specific anchoring, leading to enhanced photoluminescence.

WASCO compares conformational ensembles of intrinsically disordered proteins using a Wasserstein-based statistical metric to detect residue-level differences.