Anja Machate

This study characterizes the phenotype of adult zebrafish lacking atoh7, showing complete blindness and anatomical changes in the visual system.

The paper uses single-cell RNA sequencing to study zebrafish retina regeneration, identifying transcriptional changes and fate decisions in Muller glia and progenitors.

The paper monitors the endogenous Fgf8a gradient in zebrafish gastrulation and confirms its role as a morphogen by showing its graded distribution and signaling effects.

This study shows that lrrk2 knockout in zebrafish causes dopamine and serotonin catabolism changes, reduced cell proliferation, and impaired neuronal regeneration.

The paper investigates how lineage restriction at the midbrain-hindbrain boundary occurs through cell-fate plasticity, adhesion, and sorting, revealing mechanisms involving N-cadherin and Eph-Ephrin signaling.