Michael Brand

The paper simulates Fgf8a gradient formation in zebrafish epiboly using reconstructed 3D geometries to show that pore connectivity affects gradient shape and stability.

This paper shows that Heparan Sulfate Proteoglycans (HSPGs) in the extracellular matrix bind Fgf8, altering its diffusion and signaling, and contribute to forming the Fgf8 morphogen gradient.

This study characterizes the phenotype of adult zebrafish lacking atoh7, showing complete blindness and anatomical changes in the visual system.

The paper investigates functional recovery of regenerated cone photoreceptors in adult zebrafish retinas after light-induced injury, finding restored physiological circuit functionality within 3 months.

This study shows that immune signaling is essential for retinal regeneration in adult zebrafish, with inflammation promoting Muller glia proliferation and cell regeneration.

The paper uses single-cell RNA sequencing to study zebrafish retina regeneration, identifying transcriptional changes and fate decisions in Muller glia and progenitors.

The paper monitors the endogenous Fgf8a gradient in zebrafish gastrulation and confirms its role as a morphogen by showing its graded distribution and signaling effects.

This study shows that lrrk2 knockout in zebrafish causes dopamine and serotonin catabolism changes, reduced cell proliferation, and impaired neuronal regeneration.

The paper uses single-cell transcriptomics to reveal heterogeneity in zebrafish thyroid thyrocytes and characterizes surrounding cell types.

The paper investigates how lineage restriction at the midbrain-hindbrain boundary occurs through cell-fate plasticity, adhesion, and sorting, revealing mechanisms involving N-cadherin and Eph-Ephrin signaling.