Author

Andreas Tiefenbacher

Medical University of ViennaORCID 0000-0001-7410-6164Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

Anil Baskan· 2 shared Gerda EggeriD· 2 shared Jessica KallaiD· 2 shared Kristina DraganićiD· 2 shared Theresia MairiD· 2 shared Carlos Uziel Pérez MallaiD· 1 shared Emine Atas· 1 shared Gabriel WasingeriD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCancer Biology

Anil Baskan

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Cancer BiologyCell Reports MethodsPeer-reviewedMar 30, 2026

Biobank of genetically defined murine prostate cancer tumoroids uncovers oncogenic pathways and drug vulnerabilities driven by PTEN-loss

Jessica Kalla, Thomas Dillinger, Zlata Pavlovicova…·Gerda Egger

This study establishes a murine tumoroid biobank to identify oncogenic pathways and drug vulnerabilities in prostate cancer, finding that PTEN loss drives cancer pathways and that specific compounds inhibit tumor growth.

1 citation

mouseorganoid / primary culture

𝕏 PostBluesky

Cancer BiologyMolecular OncologyPeer-reviewedMar 11, 2025

Aggressive KRAS mutations direct TGF-β response towards partial EMT in patient-derived colorectal cancer tumoroids

Theresia Mair, Philip König, Milena Mijović…·Gerda Egger

This study investigates how TGF-β affects colorectal cancer tumoroids, finding that aggressive KRAS mutations lead to partial EMT and increased invasiveness.

2 citations

humanbulk RNA-seq

𝕏 PostBluesky