Author

Jan Karlseder

Salk Institute for Biological StudiesORCID 0000-0001-7433-9750Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Aisling O’ConnoriD· 1 shared Anthony J. CesareiD· 1 shared April E. WilliamsiD· 1 shared Candy Haggblom· 1 shared Chris D. RiffkiniD· 1 shared David C.S. HuangiD· 1 shared Duncan A Baird· 1 shared Jan O. KorbeliD· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMolecular Biology

Aisling O’ConnorORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintOct 13, 2026

Escape from replicative crisis and immortalization precedes complex genome evolution

Tobias T. Schmidt, Marco Raffaele Cosenza, Tessa M. Popay…·Jan Karlseder

The paper shows that escaping replicative crisis and achieving immortality precedes complex genome evolution in cancer cells.

DOI 10.64898/2026.10.09.758087

humanwhole-genome sequencing

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Molecular BiologyNature CommunicationsPeer-reviewedSep 17, 2019

Replication stress induces mitotic death through parallel pathways regulated by WAPL and telomere deprotection

V. Pragathi Masamsetti, Ronnie Ren Jie Low, Ka Sin Mak…·Anthony J. Cesare

This study identifies two parallel pathways regulated by WAPL and telomere deprotection that lead to mitotic death in replication stressed human cells.

54 citations

humanexperimental assay

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