Author

David A. Lewis

The Francis Crick InstituteORCID 0000-0001-7434-2837Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

David A. Lewis2 papers · Cincinnati Children's Hospital Medical Center

Biology Disciplines

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Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:mouse· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Adrian ListoniD· 1 shared Alice R SavageiD· 1 shared Ananya KariD· 1 shared Andrew MuiriD· 1 shared Arianne C. RichardiD· 1 shared D. Wright· 1 shared Erick ArmingoliD· 1 shared Jessica L. QuantrilliD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperImmunology

Adrian ListonORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintJun 30, 2026

T cell receptor-ligand affinity quantitatively tunes transcriptome remodelling in vivo, inversely regulating cell division and interferon response

Veera Panova, Andrew Muir, Erick Armingol…·Arianne C. Richard

This study shows that TCR-ligand affinity quantitatively modulates transcriptome remodelling in vivo, affecting cell division and interferon response.

DOI 10.64898/2026.06.24.734351

mousebulk RNA-seq

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Cell BiologybioRxivPreprintFeb 28, 2025

CD8 T lymphocytes redeploy embryonic cell cycle control mechanisms to facilitate rapid cell proliferation

David A. Lewis, Ananya Kar, Alice R Savage…·Tony Ly

This study identifies shared cell cycle control mechanisms between CD8 T cells and embryonic stem cells, revealing similarities in cyclin expression and Emi1 function that support rapid proliferation.

1 citation

mouseproteomics

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