Lakmini S. Premadasa

This study identifies extracellular condensates (ECs) from macaques as endogenous factors that modulate HIV transcription and latency reactivation, with THC treatment altering their anti-inflammatory properties.

This study shows cannabinoids reduce m6A methylation in miRNAs of SIV-infected macaques, shifting their profile towards an anti-inflammatory state.

This study shows that epigenetic modulation of NLRP6 reduces necroptosis and gastrointestinal inflammation in HIV/SIV-infected rhesus macaques.

This paper describes a method to isolate gut-derived extracellular vesicles (ColEVs) and shows that purified ColEVs can activate the HIV LTR promoter.