Chioma M. Okeoma

This study identifies extracellular condensates (ECs) from macaques as endogenous factors that modulate HIV transcription and latency reactivation, with THC treatment altering their anti-inflammatory properties.

This study shows cannabinoids reduce m6A methylation in miRNAs of SIV-infected macaques, shifting their profile towards an anti-inflammatory state.

This study characterizes the cargo and biological properties of extracellular vesicles from HAdV-E4-infected lung epithelial cells, showing they carry viral proteins, RNAs, and DNA and can initiate infection.

This study isolates extracellular vesicles from postmortem brain tissue and uses multi-omics analysis to identify lipidomic and proteomic changes associated with substance use disorder.

The paper identifies host proteins in human semen-derived extracellular vesicles that interact with HIV Tat and NF-κB, suggesting they may repress HIV by targeting transcription factors.

This study shows that epigenetic modulation of NLRP6 reduces necroptosis and gastrointestinal inflammation in HIV/SIV-infected rhesus macaques.

This paper describes a method to isolate gut-derived extracellular vesicles (ColEVs) and shows that purified ColEVs can activate the HIV LTR promoter.

This study shows that berberine inhibits HIV infection and cervical cancer progression by blocking HIV Tat-mediated processes and cancer cell migration and invasion.