Mahesh Mohan

This study identifies APOBEC3G splicing defects in nonhuman primates that lead to different viral mutation profiles compared to humans.

This study identifies extracellular condensates (ECs) from macaques as endogenous factors that modulate HIV transcription and latency reactivation, with THC treatment altering their anti-inflammatory properties.

This study shows cannabinoids reduce m6A methylation in miRNAs of SIV-infected macaques, shifting their profile towards an anti-inflammatory state.

This study shows that epigenetic modulation of NLRP6 reduces necroptosis and gastrointestinal inflammation in HIV/SIV-infected rhesus macaques.

This paper describes a method to isolate gut-derived extracellular vesicles (ColEVs) and shows that purified ColEVs can activate the HIV LTR promoter.