Bead-based RNA Detection with Cas13a: Multi-scale Design and Validation
Abdul Muyeed Bhuiya, Siddhansh Agarwal, Carlos F. Ng, Mélanie Ott, Sungmin Son, Daniel A. Fletcher
The paper develops a bead-based Cas13a assay called SurfCas for sensitive and multiplexed RNA detection, showing it matches bulk reaction sensitivity and works in complex biological samples.
bioRxiv · Jul 28, 2026 · PreprintBioengineering