Ekaterina Samatova

This study identifies NAC's role in regulating translation elongation, cotranslational folding, and organelle targeting through sequence-specific interactions with nascent polypeptides.

The paper identifies a novel antibiotic resistance mechanism where fusA mutations slow ribosome movement when aminoglycosides are bound, preventing error cluster formation and maintaining bacterial growth.

This study computationally predicts and experimentally validates a vectorial hierarchy of cotranslational protein folding intermediates stabilized by non-native hydrophobic interactions.