Marina V. Rodnina

This study identifies NAC's role in regulating translation elongation, cotranslational folding, and organelle targeting through sequence-specific interactions with nascent polypeptides.

The paper identifies a novel antibiotic resistance mechanism where fusA mutations slow ribosome movement when aminoglycosides are bound, preventing error cluster formation and maintaining bacterial growth.

This study computationally predicts and experimentally validates a vectorial hierarchy of cotranslational protein folding intermediates stabilized by non-native hydrophobic interactions.

The paper identifies a biosynthetic gene cluster in Rhodococcus fascians that produces lydiamycin A, a novel HPS-containing macrocyclic pentapeptide with antibacterial activity against peptide deformylase.

The paper characterizes conformational changes in human 48S translation initiation complexes during start codon recognition using cryo-EM and kinetic methods.

The paper quantifies translational readthrough (TR) in Drosophila and shows it regulates the Traffic Jam transcription factor's function in a tissue-specific manner, impacting neuronal integrity and reproductive health.

This study reveals how GTP hydrolysis by EF-G drives ribosome-tRNA movement through structural changes visualized by cryo-EM.

This study examines how antibiotics affect ribosomal subunit dynamics during translocation, showing varying impacts on SSU movements depending on the antibiotic type.

This study identifies eEF3's role in promoting tRNA dissociation from the E site during translation elongation in fungi, revealing structural insights into the yeast translation cycle.