Thomas L. Schwarz

This study shows that Dsn1 and Ndc80 are essential for postmitotic neuron survival, distinct from their role in synaptogenesis, and identifies domain-specific functions in neuronal viability.

This study identifies SARM1 as a key driver of retinal ganglion cell degeneration in ADOA and shows its suppression prevents degeneration phenotypes.

The paper identifies small molecule regulators of biological pathways by matching compound effects to known pathway phenotypes in public cell image data.

The paper shows that Pink1 mRNA is transported with mitochondria and tethered by SYNJ2BP and SYNJ2 to support local mitophagy in neurons.