Author

Whitney S. Gibbs

Boston Children's Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Thomas L. SchwarziD· 2 shared Adamantios MamaisiD· 1 shared Alexis Riley-DiPaoloiD· 1 shared Angelika Bettina HarbaueriD· 1 shared Anwesha SanyaliD· 1 shared Austin Fajfer· 1 shared Catherine G. Zykoski· 1 shared Chen DingiD· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersNeuroscience

Thomas L. SchwarzORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Loss of SARM1 protects against retinal ganglion cell degeneration in Autosomal Dominant Optic Atrophy

Chen Ding, Papa S. Ndiaye, Sydney R. Campbell, Michelle Y. Fry, Jincheng Gong, Sophia Rose Wienbar, Whitney S. Gibbs, Philippe Morquette, Luke H. Chao, Michael Tri H. Do, Thomas L. Schwarz

This study identifies SARM1 as a key driver of retinal ganglion cell degeneration in ADOA and shows its suppression prevents degeneration phenotypes.

bioRxiv · Sep 30, 2024 · PreprintNeuroscience

The LRRK2 kinase substrates Rab8a and Rab10 contribute complementary but distinct disease-relevant phenotypes in human neurons

Adamantios Mamais, Anwesha Sanyal, Austin Fajfer, Catherine G. Zykoski, Michael Guldin, Alexis Riley-DiPaolo, Nitya Subrahmanian, Whitney S. Gibbs, Steve Lin, Matthew J. LaVoie

This study shows that Rab8a and Rab10 deficiencies cause distinct lysosomal and Golgi defects in human neurons, with opposing effects on lysosomal pH and proteostasis of α-synuclein and tau.

Stem Cell Reports · Feb 1, 2024Peer-reviewedNeuroscience

Neuronal mitochondria transport Pink1 mRNA via Synaptojanin 2 to support local mitophagy

Angelika Bettina Harbauer, J. Tabitha Hees, Simone Wanderoy, Inmaculada Segura, Whitney S. Gibbs, Yiming Cheng, Martha Ordonez, Zerong Cai, Romain Cartoni, Ghazaleh Ashrafi, Chen Wang, Fabiana Perocchi, Zhigang He, Thomas L. Schwarz

The paper shows that Pink1 mRNA is transported with mitochondria and tethered by SYNJ2BP and SYNJ2 to support local mitophagy in neurons.

Neuron · Feb 24, 2022Peer-reviewedNeuroscience