Author
University of California, San FranciscoORCID 0000-0001-7541-6789Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Jessica Mella, Abigail Hein, Navraj S. Lally…·Abigail L. Buchwalter
The paper identifies cardiomyocyte-specific vulnerabilities to LMNA mutations using saturation mutagenesis in hiPSCs and cardiomyocytes, revealing how lamin polymer disruption leads to disease.
Tracy A Knight, Jessica Mella, Daniel Chen…·Abigail L. Buchwalter
This study shows that emerin loss impairs MyoD-driven differentiation of human iPSCs into skeletal myotubes by affecting PRC2-mediated gene regulation.
Jessica Mella, Regan F. Volk, Balyn W. Zaro, Abigail L. Buchwalter
The paper identifies sequences affecting emerin's secretory trafficking, showing C-terminal tags and hydrophobic domains influence its lysosomal fate, while an ER retention motif stabilizes it.