Author

Abigail E. Hein

University of California, San FranciscoORCID 0000-0002-2477-6327Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell-cell communication· 1 Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Abigail L. BuchwalteriD· 1 shared Andrew Paul LandstromiD· 1 shared Bao ThaiiD· 1 shared Cathy YangiD· 1 shared Jessica MellaiD· 1 shared Julia ConradiD· 1 shared Ke WuiD· 1 shared Megan S OstrowskiiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCell Biology

Abigail L. BuchwalterORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintSep 18, 2026

Cardiomyocyte vulnerability to lamin polymer disruption revealed by saturation mutagenesis

Jessica Mella, Abigail Hein, Navraj S. Lally…·Abigail L. Buchwalter

The paper identifies cardiomyocyte-specific vulnerabilities to LMNA mutations using saturation mutagenesis in hiPSCs and cardiomyocytes, revealing how lamin polymer disruption leads to disease.

DOI 10.64898/2026.09.17.752442

humanCRISPR screen

Molecular BiologyNature MethodsPeer-reviewedOct 19, 2023

Single molecule co-occupancy of RNA-binding proteins with an evolved RNA deaminase

Yizhu Lin, Samentha Kwok, Abigail E. Hein…·Stephen N. Floor

The paper introduces REMORA, a method to record RNA-protein interactions on single RNA molecules by using RNA deaminases, and shows competition between PUM1 and PUM2 for RNA binding sites.

24 citations

humanscRNA-seq