Jean Théberge

The paper examines how childhood maltreatment affects brain structure in 3,711 individuals with MDD and PTSD, finding age- and sex-specific brain morphometric differences.

IBMMA improves neuroimaging analysis by handling missing data and large datasets, revealing new brain region findings overlooked by traditional methods.

The paper examines thalamic volume differences in trauma-exposed individuals with PTSD, MDD, and controls, finding specific volume reductions and associations with symptom severity and childhood trauma.

The paper presents a WM intrinsic connectivity network template derived from 100,000 fMRI scans, showing distinct WM and GM networks with task-related activity and differences in schizophrenia.

The paper develops a reliable network template and methods to estimate individualized functional networks from resting-state fMRI data across 100k+ individuals, showing how data length and spatial resolution affect network estimation.

The paper examines myelin and microstructural changes in basal forebrain cholinergic nuclei in first-episode psychosis using neuroimaging and transcriptomic data, finding disrupted correlations and clinical correlates.

This study links higher brain glutathione levels to faster treatment response in first episode psychosis patients using 7-Tesla MRS.

The paper investigates glutamate levels and effective connectivity in the salience network of schizophrenia patients using multimodal imaging and cognitive tasks, finding links between glutamate and connectivity deficits.

The paper uses neuroimaging and gene expression data to show that hippocampal volume reductions in first-episode psychosis correlate with serotonin receptor densities and glutamate receptor gene expression.

This study identifies hippocampal subfield volume differences in PTSD and depression across 31 cohorts, finding depression has a stronger effect than PTSD, especially in CA1, with comorbid cases showing more pronounced changes.

This study identifies reduced fractional anisotropy in the tapetum region of the corpus callosum in PTSD patients using a large multi-cohort analysis of diffusion MRI data.