Chao Feng

The paper identifies developmental trajectories that organize valence-specific circuit assembly in the central amygdala using single-cell profiling and molecular analysis.

The paper shows that MEIS2 and DLX5 activate enhancers for projection neurons, while LHX6 represses them in interneurons, and a MEIS2 mutation linked to intellectual disability impairs this process.

The paper investigates how progenitor competence influences GABAergic neuron maturation in mice using single-cell transcriptomics and chromatin profiling, finding that NFIB regulates maturation competence in late-born neurons.