Ilaria Vitali

The paper shows that MEIS2 and DLX5 activate enhancers for projection neurons, while LHX6 represses them in interneurons, and a MEIS2 mutation linked to intellectual disability impairs this process.

The paper investigates how progenitor competence influences GABAergic neuron maturation in mice using single-cell transcriptomics and chromatin profiling, finding that NFIB regulates maturation competence in late-born neurons.

The paper identifies two distinct astrocyte lineages in the mouse neocortex using single-cell RNA sequencing and TrackerSeq, revealing their developmental origins and regulatory mechanisms.

The paper traces transcriptional trajectories of progenitors and neurons during mouse neocortex development, showing how molecular states from progenitors shape neuronal diversity.