Author

Arghya Deb

Broad InstituteORCID 0000-0001-7607-3941Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 1 Research Focus:protein design· 1 Assay:protein structure· 1

Frequent Co-Authors

Amit ChoudharyiD· 2 shared Rajaiah PerguiD· 2 shared Santosh Kumar ChaudharyiD· 2 shared Brian B. LiauiD· 1 shared David R. LiuiD· 1 shared Dhanushka N. P. Munkanatta Godage· 1 shared Diego Rodriguez· 1 shared Ellen WeisbergiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersSynthetic Biology

Amit ChoudharyORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Synthetic BiologyACS Central SciencePeer-reviewedApr 9, 2026

Proximity-induced rewiring of oncogenic kinase triggers apoptosis

Manuel L. Merz, Veronika M. Shoba, Rajaiah Pergu…·Amit Choudhary

This paper develops a small molecule, BRD8833, that induces BCR-ABL phosphorylation to disrupt its active site electric field, leading to loss of hyperactivity and apoptosis in BCR-ABL-dependent cancer cells.

1 citation

humanexperimental assay

𝕏 PostBluesky

Synthetic BiologybioRxivPreprintMay 10, 2025

Ultrasmall chemogenetic tags with group-transfer ligands

Vedagopuram Sreekanth, Shaimaa H. Sindi, Santosh Kumar Chaudhary…·Amit Choudhary

The paper introduces two ultrasmall chemogenetic tags, mgTag and cTag, which enable group-transfer reactions to append moieties to proteins, demonstrating their utility in cell signaling and proximity induction.

1 citation

protein structureexperimental assay

𝕏 PostBluesky