Author

Ellen Weisberg

Dana-Farber Cancer InstituteORCID 0000-0002-5679-9531Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Synthetic Biology· 1

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Amit ChoudharyiD· 1 shared Arghya DebiD· 1 shared Brian B. LiauiD· 1 shared Dhanushka N. P. Munkanatta Godage· 1 shared Hui Si KwokiD· 1 shared James D. GriffiniD· 1 shared Jennifer A. RothiD· 1 shared Jonathan B. Allen· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperSynthetic Biology

Amit ChoudharyORCID

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1 paper

Recent·Most cited

Proximity-induced rewiring of oncogenic kinase triggers apoptosis

Manuel L. Merz, Veronika M. Shoba, Rajaiah Pergu, Zachary C. Severance, Dhanushka N. P. Munkanatta Godage, Arghya Deb, Hui Si Kwok, Prashant R. Singh, Sameek Singh, Jonathan B. Allen, Wenzhi Tian, Pallavi M. Gosavi, Santosh Kumar Chaudhary, Viktoriya S. Anokhina, Ellen Weisberg, , Amit Choudhary

This paper develops a small molecule, BRD8833, that induces BCR-ABL phosphorylation to disrupt its active site electric field, leading to loss of hyperactivity and apoptosis in BCR-ABL-dependent cancer cells.

ACS Central Science · Apr 9, 2026Peer-reviewedSynthetic Biology