Author

Veronika M. Shoba

Broad InstituteORCID 0000-0003-0402-7414Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Amit ChoudharyiD· 1 shared Arghya DebiD· 1 shared Brian B. LiauiD· 1 shared Dhanushka N. P. Munkanatta Godage· 1 shared Ellen WeisbergiD· 1 shared Hui Si KwokiD· 1 shared James D. GriffiniD· 1 shared Jennifer A. RothiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperSynthetic Biology

Amit ChoudharyORCID

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1 paper

Recent·Most cited

Synthetic BiologyACS Central SciencePeer-reviewedApr 9, 2026

Proximity-induced rewiring of oncogenic kinase triggers apoptosis

Manuel L. Merz, Veronika M. Shoba, Rajaiah Pergu…·Amit Choudhary

This paper develops a small molecule, BRD8833, that induces BCR-ABL phosphorylation to disrupt its active site electric field, leading to loss of hyperactivity and apoptosis in BCR-ABL-dependent cancer cells.

1 citation

humanexperimental assay

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