Kimberly Siletti

The paper uses single-cell genomics to reconstruct developmental trajectories of 170 neuronal subtypes in the human hypothalamus across development.

The paper uses single nucleus RNA-sequencing to analyze human cortical areas, revealing cell type proportions and gene expression patterns that correlate with functional connectivity and areal specialization.

The paper constructs a single-cell chromatin accessibility atlas of the human brain, identifies cell-type-specific regulatory elements, and develops models to predict regulatory function of disease risk variants.

This study uses single nucleus transcriptomics to compare human and non-human primate cortical tissues, identifying human-specific gene expression patterns and their potential functional roles.

This study identifies 461 cell clusters and 3313 subclusters in the adult human brain using single-nucleus RNA sequencing, revealing regional diversity in neurons and astrocytes.

The paper identifies 188 cell types in the human brain using single-cell DNA methylation and 3D genome data, and develops a tool to predict cell types based on methylation patterns.

The paper develops a multi-omic single-nucleus sequencing method and framework to analyze regulatory genome diversity in human cortical cells and link it to disease risk variants.

The paper compares cellular diversity in the primary motor cortex across human, marmoset, and mouse using single-nucleus transcriptomics and epigenomics, finding conserved cell types and species-specific adaptations.

The paper generates a multimodal cell census and atlas of the mammalian primary motor cortex, revealing a unified molecular genetic landscape and cross-species taxonomy of cell types.

The paper creates a single-cell transcriptome atlas of mouse brain development, identifying over 1000 cell states and linking tumor cells to developmental states.

The paper shows Notch1a-mediated lateral inhibition creates a bistable switch for opposite polarity in zebrafish hair cells, confirmed through theoretical and experimental approaches.

The paper maps the connectome of zebrafish neuromasts, revealing specific, redundant, and hierarchical wiring patterns, and identifies Notch signaling as mediating wiring specificity.