Author

Rachel Truitt

University of Pennsylvania

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 1 Genomics· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Wenli YangiD· 3 shared Arjun RajiD· 2 shared Ian A. MellisiD· 2 shared Rajan JainiD· 2 shared Yogesh GoyaliD· 2 shared Allison CotéiD· 1 shared Arun PadmanabhaniD· 1 shared Benjamin Aaron GarciaiD· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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3 shared papersGenomics

Wenli YangORCID

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Author profile →

3 papers

Recent·Most cited

Cell type determination for cardiac differentiation occurs soon after seeding of human induced pluripotent stem cells

Connie Jiang, Yogesh Goyal, Naveen Jain, Qiaohong Wang, Rachel Truitt, Allison Coté, Benjamin L. Emert, Ian A. Mellis, Karun Kiani, Wenli Yang, Rajan Jain, Arjun Raj

The paper investigates cell type determination during cardiac differentiation of hiPS cells, finding that cell type specification begins shortly after seeding and is cell-autonomous.

Genome biology · Apr 5, 2022Peer-reviewedGenomics

SARS-CoV-2 ORF8 encoded protein contains a histone mimic, disrupts chromatin regulation, and enhances replication

John Kee, Samuel Thudium, David M. Renner, Karl M. Glastad, Katherine C. Palozola, Zhen Zhang, Yize Li, Joseph Cesare, Yemin Lan, Rachel Truitt, Fabian L. Cardenas‐Diaz, Darrell N. Kotton, Konstantinos–Dionysios Alysandratos, Xianwen Zhang, Xuping Xie, , Erica Korb

bioRxiv · Nov 10, 2021 · PreprintGenetics

Responsiveness to perturbations is a hallmark of transcription factors that maintain cell identity

Ian A. Mellis, Hailey I. Edelstein, Rachel Truitt, Yogesh Goyal, Lauren E. Beck, Orsolya Symmons, Margaret C. Dunagin, Ricardo Linares-Saldana, Parisha P. Shah, Juan A. Pérez-Bermejo, Arun Padmanabhan, Wenli Yang, Rajan Jain, Arjun Raj

The paper identifies transcription factors that maintain cell identity by analyzing their responsiveness to perturbations in human iPSC-derived cardiac myocytes and fibroblasts.

Cell Systems · Aug 4, 2021Peer-reviewedSystems Biology