Author

Miguel Betegon

Howard Hughes Medical InstituteORCID 0000-0001-7625-6190Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:ATAC-seq· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:Hi-C· 1 Organism:human· 1 Organism:mouse· 1 Organism:non-human primate· 1

Frequent Co-Authors

Bilge Esin ÖztürkiD· 1 shared Brett C. Hogle· 1 shared Daniel ElnataniD· 1 shared David A. AgardiD· 1 shared Fabian Köchl· 1 shared Franco Revelant· 1 shared Haley N. JanowitziD· 1 shared Hamzah AweidahiD· 1 shared

Activity by Year

2017-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperBioengineering

Bilge Esin ÖztürkORCID

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2 papers

Recent·Most cited

BioengineeringbioRxivPreprintMay 17, 2026

Structural dynamics insights into principles underlying the fitness of new broadly potent AAVs

Molly E. Johnson, Bilge Esin Öztürk, Thomas H. Tugwell…·Leah C. Byrne

The paper develops a new AAV engineering workflow, scAAVengr-Hunt, to create potent vectors and identifies a structural mechanism underlying their broad species and tissue potency.

1 citation

non-human primatemouse

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Molecular BiologyeLifePeer-reviewedJul 25, 2017

Symmetry broken and rebroken during the ATP hydrolysis cycle of the mitochondrial Hsp90 TRAP1

Daniel Elnatan, Miguel Betegon, Y.X. Liu…·David A. Agard

The paper shows ATP hydrolysis in TRAP1 is sequential and asymmetric, with conformational flipping during the cycle to remodel client proteins.

79 citations

experimental assay

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