Yanxin Liu

This study identifies the flexible N-terminal domain of Sorcin as a critical regulator that enhances Ca2+ responsiveness by stabilizing its active conformation through dynamic contacts.

This study uses long-timescale molecular dynamics simulations to show that Ca2+ binding shifts pre-existing active states in Sorcin rather than inducing activation de novo.

This study investigates calcium-induced Sorcin aggregation using stopped-flow light scattering, finding that aggregation is reversible, cooperative, and concentration-dependent.

This paper characterizes the biochemical properties of cyanobacterial HtpG from Synechococcus elongatus PCC 7942, showing it forms dimers and has higher ATPase activity than E. coli HtpG.

The paper shows ATP hydrolysis in TRAP1 is sequential and asymmetric, with conformational flipping during the cycle to remodel client proteins.