Author

Heesun Kim

University of Massachusetts Chan Medical SchoolORCID 0000-0001-7643-4516Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Organism:C. elegans· 2 Approach:experimental assay· 2

Frequent Co-Authors

Craig C. MelloiD· 2 shared Darryl ConteiD· 2 shared Meng‐Qiu DongiD· 2 shared Yue‐He DingiD· 2 shared Gangming ZhangiD· 1 shared Mei-Qing Zuo· 1 shared Shan LuiD· 1 shared Yonghong Yan· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 24 mutual co-author links

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2 shared papersMolecular Biology

Craig C. MelloORCID

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2 papers

Recent·Most cited

HDAC1 SUMOylation promotes Argonaute directed transcriptional silencing in C. elegans

Heesun Kim, Yue‐He Ding, Gangming Zhang, Yonghong Yan, Darryl Conte, Meng‐Qiu Dong, Craig C. Mello

This study shows that SUMOylation of HDA-1 in C. elegans is required for Argonaute-directed transcriptional silencing by facilitating interactions with the NuRD complex and nuclear Argonaute HRDE-1/WAGO-9.

eLife · May 17, 2021Peer-reviewedMolecular Biology

PIE-1 promotes SUMOylation and activation of HDAC1 during the C. elegans oogenesis

Heesun Kim, Yue‐He Ding, Shan Lu, Mei-Qing Zuo, Darryl Conte, Meng‐Qiu Dong, Craig C. Mello

The paper shows PIE-1 promotes SUMOylation and activation of HDAC1 in C. elegans oogenesis, enhancing Argonaute-mediated surveillance.

bioRxiv · Aug 17, 2020 · PreprintMolecular Biology