Molecular BiologyCellPeer-reviewed
Evolutionary persistence of DNA methylation for millions of years after ancient loss of a de novo methyltransferase
Sandra Catania, Phillip A. Dumesic, Harold Pimentel…·Hiten D. Madhani
The paper shows that DNA methylation persists in Cryptococcus neoformans despite the loss of a de novo methyltransferase, with methylation patterns maintained through replication and natural selection.
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