Impaired spatial coding and neuronal hyperactivity in the medial entorhinal cortex of APP NL-G-F mice
Gustavo A. Rodriguez, Eva F. Rothenberg, Oliver Shetler, Andrew Aoun, Lorenzo Posani, Srujan V. Vajram, Thomas G. Tedesco, Stefano Fusi, S. Abid Hussaini
This study examines how advanced amyloid beta pathology in APP NL-G-F mice affects spatial coding and neuronal activity in the medial entorhinal cortex, revealing impaired spatial information processing and hyperactivity.
bioRxiv · Nov 26, 2024 · PreprintNeuroscience