Author

Mathieu Herman

Columbia University Irving Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:electronic health records· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Alex R. BautistaiD· 1 shared Alice BuonfiglioliiD· 1 shared Alison RinderspacheriD· 1 shared Andrew A. SprouliD· 1 shared Andrew AouniD· 1 shared Angeliki MelaiD· 1 shared Anna Sophia MonzeliD· 1 shared Çağhan KızıliD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperNeuroscience

Alex R. BautistaORCID

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2 papers

Recent·Most cited

Lateral Entorhinal Cortex Dysfunction in Alzheimer's Disease Mice

Radha Raghuraman, Andrew Aoun, Mathieu Herman, Oliver Shetler, Eden Nahmani, S. Abid Hussaini

This study shows that AD pathology in the lateral entorhinal cortex (LEC) causes hyperactive neurons with poor firing fidelity and object coding defects, leading to LEC-specific memory impairments in a transgenic mouse model.

bioRxiv · Apr 15, 2024 · PreprintNeuroscience

A pharmacological toolkit for human microglia identifies Topoisomerase I inhibitors as immunomodulators for Alzheimer's disease

Verena Claudia Haage, John F. Tuddenham, Natacha Comandante-Lou, Alex R. Bautista, Anna Sophia Monzel, Rebecca Chiu, Masashi Fujita, Frankie G. Garcia, Prabesh Bhattarai, Ronak Patel, Alice Buonfiglioli, Juan F Idiarte, Mathieu Herman, Alison Rinderspacher, Angeliki Mela, , Philip L. De Jager

The paper identifies Topoisomerase I inhibitors as immunomodulators for Alzheimer's disease by characterizing their effects on human microglial subtypes in vitro and in a zebrafish model.

bioRxiv · Feb 6, 2024 · PreprintNeuroscience